"The Great Hunt" is an FS2 mission.
There's only 2 missions I can think of where the Lucifer stays around long enough to be vulnerable, but I don't know if the invincible flag has been left out in either case. There's "Playing Judas" and the mission where you have to escort the scientists from the GTSC Rosetta in 2 Elysium class transports, and the Lucifer jumps in. I can't remember the name of the second mission I mentioned, but in that case, if the invincible flag is missing, and you find a way to deal with all of the Scorpions and Basilisks its sends at you, and either knock out enough weapons to make a safe zone near the hull, or find a blind spot, then all you'd need to do is plug away for a half hour or so (at 4x time) and eventually, BOOM!
Later!