From practical perspective, it would be beneficial to move the weapons systems to the wingroots or even directly to the fuselage. The more mass you have far from the center of gravity, the bigger moment of inertia the ship is going to have, which directly affects the maneuverability of the ship. Thrusters, if they are to be used for maneuvering as well as propulsion, can benefit from being placed far from the CoG, but then again putting the engines on the ends of long levers creates all sorts of engineering problems with torque and stuff, which causes unnecessary structural stress and you end up needing to make the wings stronger and heavier than necessary.
Also, placing propulsion systems to significant distance from the center of gravity has other issues, especially for a military vessel. Consider what happens if one of the wings is hit and the stuff on the end of it is blown away... the fighter would be able to still use two of the engines (if upper starboard engine is blown away, lower starboard and upper port engines could still be used), but it means that if just one of the engines suffers damage, it's going to have the same effect as knocking out two engines would have. And if two engines are knocked out you're dead in the water because you have no way to counter that kind of asymmetric thrust and would just end up spinning wildly... If the thrusters were closer to the center of gravity, the problem wouldn't be as severe and possible attitude controllability problems could be reduced with thrust vectoring and maneuvering thrusters.
Not only that, but primary weapons would always benefit from being placed as close to the sight axis due to convergence issues. So from practical purposes, I would recommend at least moving the primaries to the wing roots. Or alternatively giving at least some kind of nose-mounted gun, because that wing span is going to make close quarters fighting with primaries a pain in the ass, as long as the dynamic convergence option isn't available.
Of course, Rule of Cool overrides these problems to certain extent, but the primaries realyl should be closer to the center. IMHO, anyway.
