Well the idea of husks from other species sounds good, makes sense as they wouldn't all be human. Also Melee combat will now play a part in combat, each team member will have a unique melee attack, Sheppard will have a standard melee and a "powerfull" one. I am in 2 minds about melee, while yes i did think the attacks in the previous games were dull and not very convincing, i think it should only play a very minor part.
Also about Cerberus being the enemy, that makes sense as well, as the 2 endings for ME2, even if you keep the base you technically still well, tell the illusive man to go shove it and this is bioware, their games normally always has the good ending as cannon.