I've encountered the same belligerent attitude towards vaccines at my work place. For the most part, these are people who very much do NOT line up with me ideologically or politically, but it is disheartening to watch just the same. We have been working remotely for the most part, and we have an online meeting at the end of the day to go over accomplishments, challenges, and in general try to simulate "water cooler" banter. It's pretty banal. But I've used it a couple times to try and cattle prod people into getting their shots.
My family have some friends who work for the city (not elected, just working stiffs like the rest of us) who occasionally get the inside scoop before the news does. Last week she texted us that the city still had a bunch of vaccine doses left over and they were going to have to toss them soon because not enough people had shown up that day, and they were already at least partially thawed. I kid you not, first response I get was from a degreed engineer asking me, "So, when I grow a third eye on my forehead 'cuz a this thang, do I just come talk to you about it?"
I mean, when you are dealing with this level of willful ignorance, what the hell are you supposed to do? Laws of logic and reason don't apply.