Hmm actually maybe in FS physics (realistically it can be done) we can't bridge star systems, but theres no gurantee that in the middle of nowhere there will be a jumpnode.
Why do all jumpnodes lead to a SYSTEM and not to the middle of nowhere? Maybe a node to nowhere, and then a node back to known space (say beyond the nebula)? Keep sending probes, theres gotta be one
But anyway, what about lightspeed communication? If we did this eve online style or BSG cylon style its rather easy. Bring their memory to a new body.
But if we insist on keeping things 100% canon, I still don't see why they would be completely cut off.
As seen in several missions, notably escaping capella (where command tells you to get out, clearly from out system), apparently comms can bridge the gap.
Therefore, the families can opt to all enter cryogenic sleep and wake up when the portal is up. Or if that doesnt sound too appealing, at least chat. Sure, laggy and all but can be done.
Question about in system warp. You know, we press alt-j or whatever to end mission? can't that warp be used INTERSYSTEM? Or no?
Its slow, takes many many warps but gets the job done.