I'm unable to destroy the first enemy ship (NTD Uhuru) in The King's Gambit. It jumps out extremely quickly, and (as Joshua stated), the Mjolnirs miss their shots completely.
I tried ordering my allies to disable it and to destroy it. Neither attempt changed the results. I bombed the engines and TAGged the Destroyer. None of these attempts changed the result.
The ship arrives at 0:10, and leaves at 01:13. 1 minute is far too little time to take down an Orion with blind Mjolnirs.
(I'm playing on Normal Difficulty)
edit: I might have talked too early. I tried a loadout with Stilettos and just barely managed to disable it before it left. The Deimos afterwards was a bit difficult but manageable (because I needed to rearm, so some time was lost)
edit 2: Still find it too difficult to kill it regardless.