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Off-Topic Discussion => General Discussion => Topic started by: aldo_14 on November 15, 2006, 05:01:21 am

Title: Paper cut? Suck it!
Post by: aldo_14 on November 15, 2006, 05:01:21 am
http://www.newscientist.com/article.ns?id=dn10514

Quote
Natural-born painkiller found in human saliva
Saliva from humans has yielded a natural painkiller up to six times more powerful than morphine, researchers say.

The substance, dubbed opiorphin, may spawn a new generation of natural painkillers that relieve pain as well as morphine but without the addictive and psychological side effects of the traditional drug.

When the researchers injected a pain-inducing chemical into rats’ paws, 1 gram of opiorphin per kilogram of body weight achieved the same painkilling effect as 3 grams of morphine.

The substance was so successful at blocking pain that, in a test involving a platform of upended pins, the rats needed six times as much morphine as opiorphin to render them oblivious to the pain of standing on the needle points.
Anti-depressive angle

“Its pain-suppressive effect is like that of morphine,” says Catherine Rougeot at the Pasteur Institute in Paris, France, who led the research. “But we have to test its side effects as it is not a pure painkiller,” she says. “It may also be an anti-depressive molecule.”

Rougeot and colleagues discovered that opiorphin works in nerve cells of the spine by stopping the usual destruction of natural pain-killing opiates there, called enkephalins.

Opiorphin is such a simple molecule that it should be possible to synthesise it and produce large quantities without having to isolate it from saliva, Rougeot explains. Alternatively, it might be possible to find drugs which trigger patients’ bodies to produce more of the molecule themselves.


I was sure this was already discovered, though.
Title: Re: Paper cut? Suck it!
Post by: Colonol Dekker on November 15, 2006, 05:09:07 am
In todays Metro too, Whats it called, Opiorphin?  Yep this was mentioned a few eeks back too in general conversation  :yes: Kudos to Spittle..
Title: Re: Paper cut? Suck it!
Post by: Taristin on November 15, 2006, 10:04:49 am
And people thought me weird for licking small wounds on my hands, or arm... >..>;;
Title: Re: Paper cut? Suck it!
Post by: Colonol Dekker on November 15, 2006, 10:12:37 am
Taristin, your title both confounds and scares me..........
Title: Re: Paper cut? Suck it!
Post by: Hippo on November 15, 2006, 12:09:48 pm
Opiorphin... Opium plus morphine?


and you're reading WAY too far into Raa's title.
Title: Re: Paper cut? Suck it!
Post by: Janos on November 15, 2006, 03:50:16 pm
Is this news?
Title: Re: Paper cut? Suck it!
Post by: Flipside on November 15, 2006, 03:51:28 pm
According to the New Scientist, yes, but I've known this, quite literally, for decades....odd.
Title: Re: Paper cut? Suck it!
Post by: achtung on November 15, 2006, 07:33:45 pm
Well, I'll start licking my wounds now.  Just like Cats, Dogs, always have.
Title: Re: Paper cut? Suck it!
Post by: Goober5000 on November 15, 2006, 07:57:58 pm
Wow, kissing a boo-boo really does make it all better. :)
Title: Re: Paper cut? Suck it!
Post by: Hippo on November 15, 2006, 08:11:18 pm
spitting at it moreso!
Title: Re: Paper cut? Suck it!
Post by: Stealth on November 15, 2006, 08:57:03 pm
perhaps that's why dogs lick their wounds when they get hurt?
Title: Re: Paper cut? Suck it!
Post by: KappaWing on November 15, 2006, 09:38:12 pm
Yeah, thats been known for a long time in animal saliva.

BTW why did Raa change his name to Tarstin?
Title: Re: Paper cut? Suck it!
Post by: achtung on November 15, 2006, 11:17:16 pm
Yeah, thats been known for a long time in animal saliva.

BTW why did Raa change his name to Tarstin?
The admins changed his name to Taristin.
Title: Re: Paper cut? Suck it!
Post by: KappaWing on November 16, 2006, 04:37:28 pm
Yes but why?
Title: Re: Paper cut? Suck it!
Post by: Flipside on November 16, 2006, 04:42:31 pm
Because the upgraded Forums wouldn't accept the apostrophe in his old Raa Tor'h name so he chose to have a new one instead.
Title: Re: Paper cut? Suck it!
Post by: Goober5000 on November 16, 2006, 04:50:24 pm
Actually, it was because he had gotten his name changed to Taristin everywhere else. :) The apostrophe problem happened about a year before that.
Title: Re: Paper cut? Suck it!
Post by: KappaWing on November 16, 2006, 05:21:34 pm
Ok so he got it changed eveywhere else. Why did he do that?  :P
Title: Re: Paper cut? Suck it!
Post by: Taristin on November 16, 2006, 05:41:56 pm
Because I am a believer that names should change to reflect changes in people.
Im no longer a Raa... just as Raa was no longer Raa Tor'h, and that was no longer *shudder* snipes.
People change... and a new name, to me, is a bit of a start over. Despite this incarnation being a bit bitter and disallusioned.
Title: Re: Paper cut? Suck it!
Post by: KappaWing on November 16, 2006, 05:53:07 pm
Bitter and disillusioned? What's been troubling you?
Title: Re: Paper cut? Suck it!
Post by: Turey on November 16, 2006, 06:07:15 pm
Despite this incarnation being a bit bitter and disallusioned.

Really? I couldn't tell.  :rolleyes:

Anyways, I've always licked my wounds and will continue to do so.
Title: Re: Paper cut? Suck it!
Post by: Taristin on November 16, 2006, 07:18:09 pm
's a slow process, becoming bitter. You dont notice it, but looking back at times when you were more playful, laughed and smiled more... and then seeing now. Its depressing. People have this way of being hugely hypocritical and that always gets me. Every time.
Title: Re: Paper cut? Suck it!
Post by: Prophet on November 18, 2006, 02:41:29 pm
Your thoughts are familiar, Taristin. I too wonder sometimes, if it is the world that has changed, or I.
It is both, that are changing, and are changing still.
I embrace the memories of happier times, but know that they are gone.
And I steel myself for what is yet to come...

Meh. I'm just depressed. World's a *****.
Title: Re: Paper cut? Suck it!
Post by: Descenterace on November 19, 2006, 02:43:26 am
Why am I getting a mental image of a pair of goths writing crappy poetry...
Title: Re: Paper cut? Suck it!
Post by: Prophet on November 19, 2006, 04:27:48 am
I don't know why. Because I'm not a goth. And that wasn't supposed to be poetry, just something strange to fit my alter-ego as a all-knowing mystic figure sitting in a dark room. :nervous: