I suppose that if you wanted to, you could extend a campaign by having the pilot subject to acceleration to a high percentage of the speed of light (I don't know how you'd do this, some story about being flung away by a Knossos portal or secret Shivan device or GTI experiment). That way, relatavistic distortion would come into account, and when the pilot comes to a stop (enters a stars gravitational influence and is slowed down and dragged into a spiralling orbit, rescued by a pursuing ship etc.) he'd find that the universe around him has advanced at a greater rate.
Just an idea to throw around I guess.