alien swarm, possibly tf2 (it came with orange box, but i never play it, prefer
fortress forever)
and for those up for mods (and by that i mean modules

),
modular combat for hl2:ep2
its an action rpg based on hl2 deathmatch, get exp. for kills and buy upgardes like jet pack, teleport, minions etc.
comes with several custom maps, co-opertative mode (you fight generated monsters from half-life 2), team deathmatch (combine vs rebels vs apature) and deathmatch.
for 40k'ers there is
exterminatus
neotokyo(ghost in the shell inspired CS-play-alike[or so i've heard]) is fun, if somewhat dead (i have been called a jihadist in this game for my prediliction for dieing just
after throwing a grenade...which is VERY deadly)
eternal silence is fs2 meets half-life
to sum it up, in order of preference: neotokyo, alien swarm, eternal silence, modular combat, fortress forever, exterminatus, tf2