I've also run into the freezing problem on the turkey-shoot mission of Derelict.
With command lines on:
- A Loki had done the explosion roll and was just about to blow up
- I was remote-viewing Tachyon wing from external view when the first pirate wing arrived
- I was remote-viewing the Haulian (I think), and I think the first set of pirates had arrived.
With command lines off:
- I got through most of the mission just fine, except Hercules fighters were invisible aside from engine glows; so when the last wing jumped in, the Haulian died. I rammed one of them twice, and the second time, on the rebound, FS2 closed.
Strangely enough it's the only mission I've run into it the freeze bug so far in Derelict.
Edit: Looks like it's caused by music (Didn't happen with -nomusic). I'll be testing w/o OGG music.