I have one and use it with Elite Dangerous right now.
My thoughts thus far:
It's physically big and doesn't have anything in the way of adjustments like the x52 does
It's two separate devices on the USB bus (the stick and throttle need their own plug), so some programs that are expecting to see a single HOTAS might have problems using it.
It's apparently somewhat power hungry. There are a lot of people out there who had dodgy behavior (ghost button presses, buttons that didn't stay pressed, etc) until they put it on a powered USB hub (this seemed to happen primarily with AMD systems).
The big shiny switches on the throttle base are 2-way momentary switches, they are not toggles.
The mouse 'nipple' thing on the throttle makes a really bad substitute for a physical mouse (IMO).
The software, while fairly powerful, isn't the easiest to work with. When it works and the drivers are installed, it can do a heck of a lot.
It's very sensitive, almost too sensitive. I had to increase the dead zone in E:D so the ship wouldn't start moving just by me resting my hand on the stick.
But even with these things, I don't regret buying mine, at least not yet.
