Things are not that gloomy.
Browse the bioware forums a little. the DEV's are posting there are regulary as some of the most frequent posters here. Hell, I know all the Bio DEv's by name, what they liek to eat, where they live and other stuff.
I think that Mass Effect will appear on PC too, but I'm not sure as I was not browsing ME forums, I'm haning around Dragon Age forums.
THAT is their main, holy grail project, a PC exclusive and the greatest RPG project they ever made.