The design in my head(and there are a lot of them) has four heavy beams in a Deimos like prow, so they all can target a ship in front of them, while two can still attack targets above and below.
On the upper side of the prow should be a heavy triple barreled mass driver, like the turrets on an Iowa class battle ship, while another one is situated rearward upper deck while one each is integrated starboard and portside, giving the ship massive forward firepower, but as it goes, a vasudan destroyer/battleship wouldn't mount mass drivers.
Broadside firepower would be generated by slashing beams, while there should be also torpedo tubes.
Mounted all over the hull would be AAAs, pulse turrets and the like.
I really crave to show a ship model, but I'm far from doing so...