If you're stuck using the keyboard, it's best to quickly pick up all appropriate shortcuts. To whit,
Shift + arrow keys = select one char at a time
Shift + Ctrl + arrow keys = select one word at a time (it uses spaces to detect words, so not always useful)
Shift + End / Shift + Home = select from cursor position to end of current line or beginning of current line
Ctrl + arrow keys = move cursor one word at a time
End / Home = move cursor to end of line / beginning of line
Ctrl + Backspace / Ctrl + Del = delete entire word before / after cursor position
Click + hold Shift + Click = select from first click thru second click
Ctrl + Click = select / deselect individual entries (can be used for great win in combination with Shift-clicking, e.g., I want from here thru here except these two)
Ctrl + X, C, V = Cut, Copy, or Paste the currently selected items
Alt+Spacebar = bring up program menu in the top left (yeah the one that you used to be able to get in Windows 3.1 by clicking the - sign on the top left)
Alt+Spacebar+M = select the move option from the program menu, allowing you to then use the arrow keys (or mouse) to place your window on the screen. Especially useful if your program opened up off-screen for whatever reason.
Alt+F = File menu. add S to save, A to save as, C to close, O to open
Alt+E or V, etc.. opens Edit, View, etc...
Note that I typed all of that up from memory, and there's a million other shortcuts out there, many of which I regularly use without thinking. The only thing the mouse can do that comes close is gestures, and that's only just beginning to be widely supported IIRC... except the Macs may have had it for a while. But it still can't touch a keyboard, only add to the keyboard's awesomeness.
Not that I'm disputing that this is still a PITA, but with shortcuts it's a rather manageable pain in the ass...
For example, I once had to save a few hundred .TIFF clipart files on an old system 8 or 9 Mac as a different type of TIFF that was compatible with the MS software my dad was using. I wasn't aware of any batch method of doing this, so I did it all by hand. It took me between half an hour to an hour, but it probably would have taken an average user the better part of a day. Why? Keyboard shortcuts. Alt+F+O, down arrow to next file, enter, Alt+F+A, press the appropriate combo to change filetype (I believe Alt+T, down arrow), then Alt+A, home, to add a prefix to the filename (new_ or somesuch), press enter, rinse, repeat.
After the first 20 or so, you begin to take ~3 seconds max to get this done, as you've developed a routine. You could probably go faster, but you do need to be sure not to make mistakes whilst processing.
The same approach, when taken with editing tedious text-based config files, will cut down your workload immensely. Although it will still be a PITA.
I'm assuming the reason you still wish for mouse control is that there's no way to have a live preview of the changes you are making, and no way to precisely place an object where you want it by simply giving raw coordinates, unless you're just a genius, or copying from something else that's in approximately the same location as the object that you are placing.
Any way to edit the appropriate table files from within a preview application in a notepad-esque window? i.e., open the file, see the model and everything on it, decide you want to edit the glowpoints, tell the app to do so, get a notepad window, and fudge with the numbers, whilst getting a live output? How about the ability to copy a coord to the clipboard when clicked by the mouse? You'd need a way to orient which way the coord is "facing" so to speak, but that'd be a charm..
Pipe dream? Yeah, I figured.
