I loved ME3 multiplayer but I think 'use primer use detonator' is probably not actually interesting gameplay any more. It was fun for a shockingly good tacked-on coop mode for a story driven third person shooter, and the biotic detonation sound effect was so satisfying. But I don't think it could carry a whole game for me.
It works better in the context of a single player RPG, such as Dragon Age: Inquisition
or Divinity: Original Sin 1 & 2
, when it adds another layer to your party composition.
To have definite primers and detonators is actually better than having a chance driven system, ala Persona 5 (if you have unlocked required level of Character Bonds party members can follow-up your attacks), or semi-chance driven system, ala Trails of Cold Steel
(if your currently controlled character is linked to another character and bond is sufficent, scoring a critical hit -which can be guaranteed by random turn order bonus- or unbalances the target -chance depending on the targets resistence to weapon types, can be influcenced by abilites- the linked character gets a follow-up move up to a full party combo attack).