Luke Perry is wandering though a world where some years previous, a deadly virus wiped out everyone over puberty.
He goes around trying to rebuilt society while the last remaining old people, who hid out in air-tight bunkers, go around purposely reinfecting people with the virus, watching how it progresses and then burning the subjects alive to kill the virus off. And a huge black guy tags along.
Jeremiah (Luke Perry) and his younger brother were told by his father, who apparently had something to do with the virus, that he had to get to Valhalla Sector and that they'd know how to stop, cure or evade the virus. At the end of the first and only season, he finds out more than he bargained for.