My setup is roughly thus;
Pinky; Shift (of course)
Hat 1; Target Hostiles/ Shift; Tgt Friendlies
Hat 2; Subsystem Targeting
Hat 3 (on Throttle); Augment Shields (fwd, back, L, R)
Fire, Fire A, Fire B; Missiles, Countermeasures, & Weapons Select
Fire C; Match Speed
Fire D; 'Burners/ Jump
Toggles 1-6; Energy Mgmt
....more or less.
I won't bother givin' a more specific description as I tend to change things up more often than I prob'ly should. But these ones tend to stay fairly similar. And I also won't bother postin' up any actual profiles as I figure is in yr best interest to actually learn to use the programming software. I've had the X36, X45, & now the X52 & I've never found a profile for any game that I was as satisfied with as one I set up myself. Just find what works for ya & roll with it.