Fallout 2 is a much different game from the first. If you don't get high agility then you've completely messed up your character, because all of your enemies are going to practically have agility maxed out (or have the special +4 movement perk). By the time you get Power Armor (assuming you aren't gaming the system), any strength penalty you took to put the points in something else is rendered meaningless since the game is pretty much over.
Oh, and the mechanics involving how accurate you are are bull**** in the second game. "You have maxed out perception, luck, small guns at 120%, and the accuracy perks? Well in that case, you have a 50% chance of hitting the guy just down the street with your military grade assault rifle -- in his leg."