Really interesting video and topic.

I will be speaking mostly about how this effects / could effect me personally if this were to become a regular thing.
It's interesting how in the video he thinks being able to skip things will make developers want to make people not want to skip. I think it might have the opposite effect, they'll think we can put 10 hours of crap into this game to add 10 hours of gameplay to the total of hours on the back of the box.
The only real reservations I have are running into walls in a game makes me play better, makes me play at my very best. I rise to challenges and overcome them. I enjoy making progress and unlocking stuff and breaking the walls down and claiming my prize for doing so. Just give me all that stuff from the get-go and it might take away some of the enjoyment from games. And yet, if I do eventually find getting hold of something is beyond my ability, that doesn't mean I don't still want it. And will hunt for ways to get it through cheats. I still for instance want to play the level on Perfect Dark you unlock for beating every level on Perfect Agent even though that is beyond my ability. Same for some of the stuff you can get hold of that I'm unable to acquire. But would I be able to reach that highest level of play again if I had nothing to unlock? Would my level of play degrade due to being able to just skip my way past things instead of having to fight my way past? I always say take the right path not the path of least resistance, but I can't control feelings. The emotions that drive me on, the determination to open up new levels and unlock things in games and the feeling of accomplishment on success. Pride and not wanting to take the path of least resistance would play their part in preventing this, but eventually I would hit that point where I felt I couldn't get through and I would skip past. Not come back tomorrow, in a week, in a month, in a year, in ten years and get past, as I have done with numerous games. Break down that wall and become a better player. One day in the future I might just get the improved version of Perfect Dark, with it's smoother framerate and the years between last playing it to improve my chances, and beat every level on Perfect Agent and claim my prize.
I also wonder if it could effect the difficulty of games and the dumbing down of games. It could further encourage the dumbing down of games. I'd like to hope it could be a positive force though, to help stop games being too easy so that those who can't get through can still get through. Difficulty levels are the way this should be combated really, but some games do not have them, or are too easy even on the top difficulty.
I can't really say if I am for or against. I can also think of positive uses I would have for it. I would love to be able to blast through an RPG to get to certain points in the game, certain parts of the story, fight certain bosses, fight certain bosses under certain conditions, that would be so much easier to set up if I didn't have to grind my way through the entire game to get there. I greatly dislike games where you can't replay levels and such. There are several games where I have a ton of saves to get around this. Like said in the video, there will be times when a level is just dross and a literal chore to play through and that can be done away with.
If such a thing starts being adopted by others and spreading, I will find it very interesting seeing how it is used and what I make of it. It's quite the puzzle trying to weigh the potential benefits and the potential negatives and trying to decide which is best for me. I don't know the answer to that question. I feel real concern and real excitement at some of the possibilities.