The Obirians' Annihilator Beam from Nodewars-2 could have.
Problem is, being a subspacial weapon (albeit shoddy and experimental) it would have attracted Shivans like moths to a lamp.
(That is, in fact, what happened -- months before the battle of Tau Ceti even occurred. The Annihilator Beam was carved in half by a Rakshasa cruiser in the Battle of Porinos.)
Meh. Both the Salvation and the Goliath would have been too slow/vulnerable to use the Annie-Beam against the Lucifer.
Someone ought to re-upload NW2 for general reading, so people know what I'm talking about.

*sigh* nostalgia
