Try cheating the Shivan Super Lasers into your loadout. It's madness.

Cheats were originally supposed to help mission designers balance a mission, although if you've already played through the whole game without cheating, of if you just want to be
God FRED, it also comes in handy.
~ + K does 100 000 hull damage. Both the Sathanas and Colossus require 10 times of ~ + K to be destroyed.
Using a Hercules with two SReds is also quite formidable. You can do huge amounts of damage and see what you're hitting.

In fact, if the ship you're flying has guns that are spaced far apart from each other, you can see what you hit even if you're firing a beam.
Here's a shot I made by cheating an SRed into my ship in The Procyon Insurgency:
