Notes: I'm operating under the assumption that TAGged ships can be precision-targeted. If not, well...that's silly. Please point out flaws, and I'm also assuming the firepower I suggest would be sufficient. If not...feel free to up the required ships accordingly. I totally forget all of the exact values involved. I'm more discussing a potential strategy rather than precisely how much force would be required to execute it.
I suppose ideally speaking - assuming only one Sath "problem", with no capship escorts - I would use an operation requiring precision timing.
First wave, surprise attack of five wings of bombers with light fighter escort , jump in close and fire off enough warheads to take out the four forward beams and the LRed.
Upon stage one completion, initiate stage two, two wings of interceptors jump in, armed with TAG missiles, as well as a pair of Orion destroyers, precision-jumped into position to have firing lines on the Fighterbay and Engine systems of the Sath, respectively. LoS on both at once if possible (not sure if it is, I forget..). Destroyer escorts also jump in at this time, a pair of Deimos' and a few Aeolus', if we can get them, as well as some Leviathans for good measure and/or distraction. Those don't have to be too precise as long as they're close enough to cover the destroyers.
Stage three, interceptors TAG the fighterbay as soon as the Orions jump in, and all available capships with LoS, as well as all available bomber wings, attack it.
Upon stage three completion, stage four, interceptors TAG the comms subsystem, and it's taken out as quickly as possible, by the same method.
Upon stage four completion, interceptors proceed to TAG the engine and navigation subsystems, same as previous.
Stage five, all remaining weapons methodically destroyed (TAGged or just fired upon manually) and all remaining subsystems attacked until destroyed.
...Then just have everything available shoot it til it explodes and run away if reinforcements arrive.
Ideally you'd have extra forces on standby in order to deal with Shivan reinforcements...but that's a fair deal of firepower required just to blow up a Sath, even being intelligent about it.
Also...if another Sath arrives? Give it up and run away. Don't be stupid.