Hey, I just installed the open thing and was trying out Topace's Renegade Resurrgence. Anyway, when I started the fist mission, if I targetted a ship the red box would appear around my target, but the lead indicator and the distance to and the 'others targetting dots' would appear several inches to the right (and usually several inches down too).
Also when I failed the mission, the primary failed indicator came up several inches to the right as well.
My computer is pretty slow (overclocked 450mhz is about all I know about it), but the gameplay itself wasn't _that_ bad. So I dunno what's going on.