In order for this to be made, a reasonable return on any investment would have to be predicted. I see two possibilities if this were to happen:
Small Scale: PC Only release. Basically, a smaller team builds FS3. Smaller team means a smaller investment. Since the genre has a perceived small audience, making a smaller investment would match and be a safer bet. The benefit to us would be a game that catered to what we like, as opposed to mass market appeal. This option would more likely yield mod tools as well, because a smaller investment by the powers at be would mean that extra time/money being spent on tools that have more value in the small audience they targeted could result in more sales. Downside is the potential for a smaller campaign/game with a limited investment.
Large Scale, AAA title: This kind of investment would require the largest audience possible. Any game with big funding needs big profit, so I simultaneuos release of both PC and console versions would make the most financial sense. Less complex controls would occur, as console controller compatibility would be a requirement. That could turn out to be a good thing, depending on how creative V gets. Plus side to us: Potentially Long campaign, more players. Down side is that mod tools will lose value as a large portion would not have any access to them, meaning time and money spent will not equal the same return on the investment.
My .02